Journal: eLife
Article Title: Adrenomedullin restores the human cortical interneurons migration defects induced by hypoxia
doi: 10.7554/eLife.108134
Figure Lengend Snippet: ( A ) Oxygen levels (PO 2 (mmHg)) in cell culture media under control conditions and following exposure to hypoxia for 24 hr in the C-chamber hypoxia sub-chamber (Biospherix; unpaired t -test, p<0.0001); ( B ) Hierarchical clustering, using Ward’s criterion, of the first three principal components of the normalized gene expression profiles of all 17,777 genes passing quality control shows clear separation of 12 and 24 hr hypoxia-exposed samples versus control and from reoxygenated samples. Bar charts: mean ± s.e.m.
Article Snippet: For these experiments, we induced hypoxia using the C-chamber hypoxia sub-chamber (Biospherix).
Techniques: Cell Culture, Control, Gene Expression